Diabetes - What To Do

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Diabetes is a degenerative, persisting disease that is caused by the body not producing enough insulin and thereby causing insulin deficiencies. You can also be insulin resistant, this health is where the cells resist the insulin's attempts to regulate blood sugar levels. The insulin hormone is produced by the pancreas and its job is to metabolize glucose, one of the original sources of the cells' energy supply. So, regardless of whether the cause is a lack of insulin or a resistance to insulin, the succeed in the body is the same: it is unable to transport enough glucose to the cells from the bloodstream. It can be even worse after meals; this is when the blood sugar levels rise as a process of digestion. The body normally self-regulates the sugar levels, a process known as homeostasis this process is activated when there is a rise in blood glucose after eating, this then releases the insulin hormone in the pancreas and when functioning properly it keeps the blood sugar levels within a safe range. When this is not functioning correctly the glucose levels remain too high. And if this continues and becomes persisting then you are ripe for an occurrence of diabetes. Many population who have diabetes are unaware of the condition. Diabetes is a cause of death, blindness and amputations; it is also the important cause of kidney and heart disease.

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How is Diabetes - What To Do

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Measuring the glucose levels in the bloodstream tests for diabetes. The main test that is used is a recurring elevated blood sugar level after an overnight fast. A fasting blood sugar value that is over 126 mg/dl on no less than 2 occasions is an indicator of diabetes. The general values are in the middle of 64 and 110 mg/dl.

You will often need at least a 4 to 5 hour Glucose Tolerance Test to check both glucose and insulin levels. Diabetic medicine is an attempt to restore blood sugar levels to as close to a general range as possible.

Effective medicine does require diabetics to be actively involved in the administration of their diet and lifestyle. While Type 1 diabetics have to be more diligent and require insulin, you can be victorious with stress management, diet, exercise, nutrition, detoxification and herbs in close to 95% of all cases.

The two main types of diabetes are: non-insulin, known as Type Ii diabetes, and insulin dependent diabetes known as Type I. persisting high blood sugar levels, along with disturbances in fat, protein, and carbohydrate metabolism, divulge both.

The most tasteless form is Type Ii diabetes and is responsible for in the middle of 90% and 95% of all cases in the Us. Due to beta cell failure, Type I diabetes do not yield enough insulin or sometimes none at all in the pancreatic islet cells. Type I normally begins in childhood, any way it can occur later in life especially if the pancreas is damaged. Type I is treated (not cured) with original medicine by administering injections of insulin with each meal to regulate the blood sugar.

Type Ii diabetes is the far more tasteless type of diabetes. It is sometimes called "insulin resistance." With Type Ii the body continues to yield insulin, but it is produced in such a way that it does not properly join together with muscles and fat to permit the glucose inside the cells to yield energy.

Gestational Diabetes is a 3rd type and it is triggered hormonally, and is normally a temporary health that will occur in women who are pregnant. It is a mild health and very manageable with diet and exercise. It very rarely requires insulin injections. Although this is temporary and mild it should be addressed because blood sugar levels that are too high can be damaging to the fetus and can impair the immune defenses of the baby.

The symptoms of Type I are inordinate urination, hunger, weight loss, inordinate thirst, dehydration and fatigue. If not treated or managed properly it can succeed in hyperosmolar coma and ketoacidosis. Ketoacidosis is a persisting state of acidity in the body and is very dangerous. This can be life-threatening and should be taken care of as a medical emergency.

Also life-threatening, and is fatal 50% of the time is a Hyperosmolar coma which also requires hospitalization. This occurs from dehydration high blood sugar levels, and/or infection or stress. So for the most part the symptoms of Type Ii are the same as Type I diabetes, with the exception of inordinate and un-healthy weight loss or gain.

Some of the warning signs for the onset of Type Ii will consist of moments of dizziness, weight gain, carbohydrate cravings rise in cholesterol levels, and an increase in blood pressure, fatigue, fainting (as an allergic reaction to a meal) and frequent fungal infections. If you are experiencing any of these symptoms go now and get medical attention. persisting high levels of glucose that can cause diabetes can lead to a whole host of other very serious health conditions.

According to a holistic health practitioner at the Clear Clinic in Mill Valley, Ca microorganisms and/or energetic imbalances that is not detected by accepted means can often cause both Type Ii and Type I diabetes. Dr. Hulda Clark also agrees with that. And what Dr. Clark suggests is zapping and cleansing. The cleansing includes the bowel, parasite, kidney, liver and metal cleanses. Also you will want to use a Zapper Mhz or Lcd or a Rife engine to make sure you have killed all the potential microorganisms and parasites.

Type I diabetes can be due to hereditary factors, so it is difficult to take preventive measures, but Type Ii which is the more prevalent can be prevented. You can through lifestyle changes that encompass an organic, natural diet, exercise, stress reduction, and use some high capability nutritional supplements for prevention and as part of treatment. Once the diet has improved then you can start some cleansing and detoxification for regaining your health.

If you have already been diagnosed with diabetes, then it is the controlling of your glucose levels that is original to avoid any supplementary complications or the disease getting worse. High blood pressure also needs to be controlled along with high cholesterol and triglyceride levels. Also seek alternative expert care for seeing problems in your heart, feet, eyes and kidneys.

The important oils of juniper, cedar and olive can help to comfort the symptoms when massaged into the lower left side of the body, this is the location of the pancreas and spleen.

For the diet, eliminate sugar, cut your fat intake, and cut straightforward carbohydrates and your protein intake. This will help to avoid any kidney damage. Herbal medicine, rehearsal and cleansing are important for an Ayurvedic approach. An example of one advent of the Ayurvedic formula involves herbal massages and herbal steam saunas, followed by cleansing and fasting. Colonics and herbal enemas are also used sometimes.

One of the herbs used by Ayurvedic physicians is Gymnema sylvestre. It is used to stimulate the pancreas to yield insulin and block sugar absorption. Other herbs that are used are: neem and bitter melon (these lower the blood sugar and stimulate the pancreas), and it also acts as a liver tonic that will help to preclude gallstones.

Chelation therapy is also useful for preventing complications that can be caused by diabetes. This creates fewer cases of kidney dialysis and blindness and reduced amputations. Also shown to be productive in reducing adult-onset diabetes is deferoamine chelation therapy. This chelates excess iron from the bloodstream. It has been shown that women who have very high levels of iron triple their risk for diabetes.

The proper diet to preclude and treat diabetes is to eliminate all sugar products (refined sugar) and these consist of corn syrup, dextrose, glucose, cornstarch, dextrin, fruit juice concentrates, fructose, malt, lactose, maltodextrin, mannitol, maltose, sorghum, sucrose, sorbitol and xylitol. Also eliminate honey, Agaves or Chicory syrup, maple syrup, caffeine and alcohol. Eliminate all junk foods, fried foods, foods that consist of white flour and eliminate sodas.

Good capability protein snacks are fresh vegetables, vegetable juice and soaked nuts. Replace the straightforward carbohydrates with involved carbs. Use whole flours, grains, legumes, and beans and fiber-rich vegetables.

And instead of eating 3 large meals daily eat 5 to 6 smaller meals throughout the day. This will help balance the blood sugar levels and will help to preclude insulin spikes after eating. A diet high in organic vegetables, small intakes of organic fruit that contains pits or seeds, and whole grains has been found to be helpful for many suffering from Type Ii diabetes. Another food that will help control blood sugar levels is Jerusalem artichokes. Eating healthy fats, like avocados, seeds, extra virgin olive oil, nuts, coconut butter and high lignin flax seed oil will also retain and help to mouth carport blood sugar levels.

Many Type Ii patients do very well on a diet that consists of 55% to 60% involved carbohydrates, 20 to 25 percent healthy fats and 15 to 20 percent protein with a minimum of 45 grams of protein per day.

Also increase your fiber intake to 40 to 50 grams of fiber daily, with 10 to 15 grams of soluble fiber. And increase your pure, filtered water intake also.

The foods that cause the many spikes in insulin levels are those that have a high glycemic rating. The foods on the low glycemic index are much better choices for those with diabetes. You can help the body to mouth low insulin and blood sugar levels by eating meals that consist of an fullness of low-glycemic foods and those foods include: fruits that consist of pits or seeds, raw, organic leafy green vegetables, yams, organic whole-grains, sweet potatoes, most legumes and nuts, poultry, buttermilk, whole grain breads, yogurt, wild caught fish, lean cuts of beef, lamb or bison.

Generally cooked foods have a higher glycemic rating than do the raw foods. Those that have a higher glycemic rating include: English muffins, cookies, white breads and bagels, commercially packaged cereals, pastries, most desserts, dried fruits including raisins, whole milk and cheese, white potatoes, peanut butter, peanuts and all processed flesh foods such as lunch meats and hot dogs.

There are a lot of herbs that have blood sugar regulating properties and can be helpful in managing the glucose levels of non-insulin dependent diabetics. Those herbs are Gymmena sylvestre, gymnesyl, fenugreek seeds, huereque, bitter melon, Jerusalem artichoke, bilberry, garlic, mulberry leaves, ginseng and olive leaves. Also useful are tonics made from ginkgo biloba and hawthorn berry.

Note: It is of original point to monitor your urine and blood sugar levels when taking herbs that lower blood sugar. Best to find an alternative health care expert to help you with this.

According to some the huerque cactus can so significantly help lower elevated blood sugar levels that Type Ii diabetes patients were eventually able to stop taking insulin. The only thing with this is after a while the body builds up a tolerance to it, so it is recommend that you stop for a month and then start back up to keep it effective. Continue to repeat this process; 4 to 6 months on and one month off. You can substitute the huerque with nopal during the month off of the huerque. The nopal is Another cactus supplement.

The juice combinations that will help to stabilize blood sugar levels includes: a blend of cucumber, string beans, parsley and watercress. Another good combo is celery, spinach and parsley, romaine lettuce, 2 carrots and spinach; cucumber, chard and celery. Drink any of the combinations once to twice a day.

The supplements that will help in managing glucose and insulin levels consist of vitamins, B-complex, C, E, B6,biotin, magnesium, potassium, chromium, important fatty acids, vanadium or vanadyl sulfate, flaxseed oil and minerals chromium, zinc, and magnesium. Still other supplements that will help are alphalipoic acid, CoQ10, amino acid complex, digestive enzymes such as lipase, protease, amylase and pancreatic enzymes. And recently it has been shown that stabilized rice bran provides important benefits for managing diabetes due to its capability to cut blood sugar levels.

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Cholesterol: Is My Heart at Risk?

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Cholesterol is a waxy steroid of fat produced in liver or intestine, used for the synthesis of hormones and cell membranes and portable in the blood plasma of all mammals. Cholesterol is a very requisite structural component of plasma membrane of mammals required for maintaining proper membrane permeability and fluidity. It is also an foremost agent required for the make of bile acids, steroid hormones and vitamin D. It is the requisite steroid synthesized by animals however, smaller amounts are also produced in plants and fungi. Cholesterol is entirely absent among prokaryotes. If its attentiveness increases in blood then the risk of cardiovascular diseases increases so its level must be kept under control. The word cholesterol has originated from a Greek word and was first discovered by Francois Poulletier de la Salle in gallstones in solid form in 1769 but, chemical identification was done by Eugène Chevreul in 1815 who gave the term cholesterine.

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How is Cholesterol: Is My Heart at Risk?

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Physiology
Cholesterol participates in the synthesis of male and female steroid hormones especially testosterone and estrogens. About 80% of the body's cholesterol is synthesized by the liver while rest comes from our diet. The major sources of dietary cholesterol are meat, fish, poultry, and dairy products. Among meat, liver is excessively rich in cholesterol content while foods of plant origin lack cholesterol. After spicy a meal, the dietary cholesterol is absorbed from the intestine and packaged inside a protein coat. This cholesterol-protein coat involved is known as chylomicron which is later stored in the liver. Liver bears the possible of regulating cholesterol levels in the blood stream. Cholesterol synthesis starts from simpler elements present in the body. In blood circulation it is portable within lipoproteins and if its level increases then the risk of atherosclerosis increases. Typically for a man weighing 68 kg the total body cholesterol synthesis is 1 g per day. The daily further dietary intake of cholesterol in the United States is 200-300 mg. The body maintains balance by minimizing the total estimate synthesized in the body if the dietary intake of cholesterol increases.

Cholesterol is also recycled, it is excreted by the liver via bile into the digestive tract. About 50% of the excreted cholesterol is again reabsorbed in the small intestine and reaches blood stream. Phytosterols can compete with cholesterol reabsorption in the intestine and thus, sacrifice cholesterol level. Cholesterol is a fat required by the body in small amounts. High blood levels of cholesterol can lead to coronary artery disease and angina. Nitrates are used to relieve angina. Most citizen require regular tests for knowing blood cholesterol levels that comprise checking of triglycerides, high density lipoproteins (Hdl), low density lipoproteins (Ldl) and total cholesterol levels.

Methods for expanding the levels of good cholesterol or lowering blood cholesterol levels comprise cholesterol reducing drugs like statins, fibrates, niacin and bile acid resins. These drugs are not able to reverse calcification and if coronary arteries are blocked then heart strike may occur. The two chief types of cholesterols are high density lipoproteins (Hdl) and low density lipoproteins (Ldl). For the sake of simplicity Hdl is determined as good cholesterol while Ldl is known as the bad cholesterol. We can stop that the bad cholesterol is responsible for forming plaques in the arteries and thus, increases the risk of heart attack. The good cholesterol on the other hand, reverses cholesterol transport by taking it out of the plaque and sending it back to blood circulation for urination via liver.

Types
Three major types of lipoproteins are found in the serum of a fasting personel namely, low density lipoproteins (Ldl), high density lipoproteins (Hdl) and very low density lipoproteins (Vldl).

1. Low density lipoproteins (Ldl) or bad cholesterol and its management

Ldl or bad cholesterol comprises 60-70% of the total serum cholesterol. It is the major atherogenic lipoprotein used in the cholesterol lowering therapy as its higher levels are dangerous. It deposits cholesterol on the walls of arteries resulting in the formation of a hard substance known as cholesterol plaque. This plaque is responsible for the hardening of arterial walls so they become narrow and the process is identified as atherosclerosis. Liver not only commerce and secretes Ldl cholesterol in the blood stream but also removes it from the blood. A large estimate of active receptors are present on the surface of liver that actively bind to the Ldl cholesterol molecules and take off it from blood. A scantness of Ldl receptors is linked with the higher level of these molecules in the blood.

A estimate of advantages are known when the levels of bad cholesterol endure allowance for example, declination in the formation of new plaques on the walls of the arteries, dismissal of existing plaques from the arterial walls, narrowed arteries attain their general shape, avoidance of rupturing of plaques which facilitates formation of blood clots and finally the risk of heart strike is reduced. A estimate of studies have indicated that the risk of heart strike diminishes by 25% for every 10% drop in the Ldl cholesterol level and it is the key factor ensuring that total blood cholesterol level has reached a safer zone. A study carried out with 4,000 individuals has confirmed that the levels of bad cholesterol and risk of heart strike were reduced to about 25% and 42%by using the drug statin. It is profitable that the daily calorie intake of fat must be reduced down to 30% and consumption distinct kinds of foods rich in carbohydrates, proteins must be increased as the body will change them into triglycerides which are later stored as fat.

Foods rich in saturated fats increase levels of Ldl cholesterol in blood stream. Fats may be classified as saturated and unsaturated fats. Saturated fats are of course ready in the meat, dairy products and some vegetable oils especially those derived from coconut, palm and cocoa. Therapeutic lifestyle changes adopted for lowering the levels of bad cholesterol comprise regular exercise, loss of excess body weight and following a diet with low attentiveness of saturated fats and cholesterol. When lifestyle changes fail to give desired results then medications are taken into consideration. Statins are the most efficient drugs giving best results for lowering the levels of bad cholesterol and also reducing the risk of heart diseases. Other drugs that can be used comprise fibrates like gemfibrozin, resins such as cholestyramine, ezetimibe and Zetia. The National make of Health, the American Heart connection and the American College of Cardiology have published some guidelines that can help the curative experts while dealing with cases of high cholesterol.

2. High density lipoproteins (Ldl) or good cholesterol and its advantages

Hdl cholesterol or the good cholesterol as it prevents atherosclerosis by extracting cholesterol from the arterial walls and disposing them through liver. High levels of Ldl cholesterol and low levels of Hdl cholesterol are linked with the risk of heart diseases. So the levels must be maintained in order to enjoy a happy and salutary life. Hdl cholesterol accounts for 20-30% of the total serum cholesterol. Since it reduces the risk of atherosclerosis its level must be checked from time to time. Both heredity and diet have a requisite corollary on a person's Hdl, Ldl and total cholesterol levels. Families with low Hdl levels are at an elevated risk of heart strike and vice versa. Lifestyle and other factors also influence Hdl levels. Hdl levels are low in individuals who smoke, are overweight, inactive and suffer from Type Ii diabetes mellitus. Hdl levels are higher in individuals who are lean, rehearsal usually and do not smoke. Estrogens also increase Hdl levels so women have high Hdl cholesterol levels as compared to men.

Lowering of the Ldl cholesterol level is however easier than elevating the levels of Hdl cholesterol. Reducing Ldl and raising Hdl levels have a beneficial corollary on an individual's health. Earlier the researchers were much focused on the ways of reducing the levels of bad cholesterol but with advancement in research it became clear that it is great to raise the levels of good cholesterol as it will automatically sacrifice bad cholesterol levels. The levels may be raised by weight loss, regular rehearsal and intake of niacin. Some studies have recommend that drugs like statin when coupled with niacin give great results and women with high levels of Hdl have reduced risk of heart attack. The average Hdl level for women must be in between 50-55 mg/dL and for men 40-50 mg/dL. The total cholesterol to Hdl cholesterol ratio can be of help in estimating the risk of atherosclerosis. An average ratio must be in between 4-5.

Studies have indicated that even a small increase in the level of Hdl cholesterol can sacrifice the risk of heart attack. For every 1 mg/dL rise in the Hdl cholesterol level the risk of coronary heart disease reduces by 2-4%. However, therapeutic lifestyle changes can help in expanding the Hdl levels. When these changes fail to give positive results then medication is taken into account. regular aerobic exercise, loss of inordinate body weight and cessation of smoking are helpful in raising Hdl levels. regular alcohol consumption for example, taking one drink per day can also help in this regard but as alcohol consumption is coupled with many adverse health effects this criterion is not taken into consideration. efficient drugs comprise gemfibrozil, estrogen and lower doses of statin. A newer medicine, fenofibrate has also given great results and is used in reducing serum triglycerides.

3. Triglycerides or very low density lipoproteins (Vldl) or ugly cholesterol and its effects

The ugly cholesterol is a triglyceride rich lipoprotein that accounts for 10-15% of the total serum cholesterol. This cholesterol is produced by liver and some remnants of Vldl seem to promote atherosclerosis similar to that of Ldl. Triglyceride is a form of fat portable to the tissue through blood. Body's majority of fatty tissue is composed of triglycerides. Serum triglycerides can be derived from two sources. The first source is the food that we consume for example, if we consume a diet rich in fats then intestine packs some of them while rest is portable to the liver. The second source is the liver itself. When fats are received by the liver, it takes fatty acids released by the fat cells and ties them in triglyceride bundles that are later utilized as fuel. There is a controversy about the fact that whether high levels of triglycerides alone are responsible for coronary heart disease or not.

Other clinical conditions oftentimes coupled with high triglyceride levels are high blood pressure, obesity, diabetes, persisting kidney, liver and circulatory disease and hypothyroidism. In some individuals elevated triglyceride levels are inherited and this health is identified as hypertriglyceridemia. The tasteless examples of hypertriglyceridemia comprise mixed hypertriglyceridemia, familial hypertriglyceridemia and familial dysbetalipoproteinemia. Hypertriglyceridemia can also occur due to some non-genetic factors like obesity, inordinate alcohol, diabetes mellitus, kidney disease and use of estrogen containing medicines like birth operate pills. The levels can be returned back to general without medication by taking the help of a physician. The first step involved in the treatment of hypertriglyceridemia includes intake of a diet low in fats with little consumption of sweets, regular aerobic exercise, loss of excess body weight, allowance of alcohol consumption and quitting smoking. In patients with diabetes mellitus efficient operate of glucose level is needed.

When medications become requisite statins, fibrates and niacin can be used. Fibrates not only sacrifice the triglyceride levels but also raise the Hdl levels and particle size of Ldl molecules. Same task is done by niacin but it lowers the levels of Lp (a) cholesterol. Statins on the other hand, sacrifice both triglyceride and Ldl levels but are ineffective in raising Hdl levels. A newly launched medicine, fenofibrate has shown promising results in lowering triglyceride and Ldl levels as well as raising Hdl levels especially in those individuals who show sub-optimal responses with fibrates. In some individuals a mixed dose of fibrate or fenofibrate along with statin is prescribed for great results.

Function

Cholesterol is needed for building and maintenance of membranes as it modulates membrane fluidity over a wide range of physiological temperatures. The hydroxyl group placed on the cholesterol molecule interacts with the polar head groups of membrane phospholipids and sphingolipids and thus, reduces permeability of membrane to protons. Within the cell membrane it also functions in intracellular transport, nerve conduction and cell signaling. Cholesterol is also very requisite for the structure and function of invaginated caveolae and clathrin coated pits in endocytosis. Recently, it has been recommend that cholesterol also plays some role in cell signaling process by assisting in formation of lipid rafts in plasma membrane. In many neurons a cholesterol rich myelin sheath is present which is derived from the compact layers of Schwann cell membrane helping in efficient nerve conduction. This layer also provides insulation. Within cells cholesterol also acts as a precursor molecule for some biochemical processes. In liver, cholesterol is converted into bile which is then stored in gallbladder. Bile is rich in bile salts which actively solubilize fat molecules in the digestive tract and thus, aid in intestinal absorption of fat molecules and fat soluble vitamins like A,D,E and K. It is also an requisite precursor molecule for the synthesis of vitamin D and steroid hormones.

Biosynthesis and Regulation

All animal cells make cholesterol but the rate of output varies depending upon the cell type and the organ involved. About 20-25% daily output of cholesterol occurs in the liver and rest in intestines, adrenal glands and reproductive organs. Synthesis of cholesterol within the body starts with one molecule of acetyl- CoA and one molecule of acetoacetyl-CoA that are hydrated to form 3-hydroxy-3-methylglutaryl-CoA (Hmg-CoA). The Hmg-CoA so formed is reduced to form mevalonate by the enzyme Hmg-CoA reductase. This step is the rate limiting and irreversible step in the cholesterol synthesis. The mevalonate so formed is converted into 3-isopentenyl pyrophosphate in three reactions that need Atp. Mevalonate is then decarboxylated to form isopentenyl pyrophosphate. Then three molecules of isopentenyl pyrophosphate collaborate together to form farnesyl pyrophosphate in the nearnessy of geranyl transferase. Two molecules of farnesyl pyrophosphate join to form squalene in the endoplasmic reticulum and the reaction is catalyzed by squalene synthase. Oxidosqualene cyclase then converts squalene to lanosterol that finally forms cholesterol. The mechanism and regulation of cholesterol was worked out by Konard Bloch and Feodor Lynen for which they received Noble Prize in Physiology or treatment in 1964.

The biosynthesis of cholesterol is under the accurate operate of the cholesterol levels but homeostatic mechanisms involved in its regulation are partly understood. A higher intake of cholesterol from food results in a net decrease in endogenous output and vice versa. The main mechanism involved comprises sensing of intracellular cholesterol by the protein Srebp (sterol regulatory element-binding protein 1 and 2) placed on the endoplasmic reticulum. In the nearnessy of cholesterol this protein binds with two other proteins namely, Scap (Srebp-cleavage-activating protein) and Insig 1. When the cholesterol level declines Insig 1 dissociates from the Srebp-Scap complex, allowing entry of this involved into the Golgi apparatus, where Srebp is cleaved by S1 and S2 proteases. These proteases are activated by Scap when cholesterol levels decline. The cleaved Srebp then migrates towards the nucleus to act as a transcription factor and here it binds to the sterol regulatory element (Sre) which stimulates transcription of many genes for example, scavenging of circulating Ldl from the blood stream by low density lipoprotein (Ldl) receptor and increase in the endogenous output of cholesterol by Hmg-CoA reductase. A larger part of this signaling pathway was worked out by Dr. Michael S. Brown and Dr. Joseph L. Goldstein in 1970s for which they received Noble Prize in 1985.

Cholesterol synthesis can be concluded when cholesterol levels are high. Hmg-CoA reductase bears both cytosolic and membrane domains. The membrane domain is sensitive for the signals responsible for its degradation. Increased attentiveness of cholesterol causes a change in the oligomerized state of domain that makes it more susceptible to destruction by proteosome. The operation of this enzyme can also be reduced by phosphorylation by an Amp activated protein kinase. Cholesterol is only slightly soluble in water and can be dissolved in water-based blood stream but travels at exceedingly small concentrations. As cholesterol is insoluble in blood it is portable in the circulatory law within the lipoprotein complexes whose outer part is made up of amphiphilic proteins and lipids. Triglycerides and cholesterol esters are carried internally. Lipoproteins provide cholesterol a soluble medium to be portable through blood and for this hypothesize lipoproteins are carried in distinct forms within blood namely, chylomicrons, very low density lipoproteins (Vldl), intermediate density lipoproteins (Idl), low density lipoproteins (Ldl) and high density lipoproteins (Hdl).

Chylomicrons are the least dense type of cholesterol transporting molecules whose shells are rich in apolipoprotein B-48, apolipoprotein C and E. They carry fats from intestine to muscles and other tissues that require fatty acids for energy. Cholesterol that is not used by the muscles remains in the form of chylomicron remnant which is later taken up by the liver through blood stream. Vldl molecules produced by the liver are loaded with triacylglycerol and cholesterol that are not needed by the liver for the output of bile acids. These molecules comprise apolipoprotein B100 and apoplipoprotein E in their shells. While transport the blood vessels cleave and Ant. Eject triacylglycerol from Idl molecules that have high attentiveness of cholesterol. Ldl molecules are the major carriers of cholesterol in the blood and each molecule contains about 1,500 cholesterol esters. The shell of Ldl molecule contains only one molecule of apolipoprotein B100 that is recognized by the Ldl receptors present on the peripheral tissues. While binding of apolipoprotein B100 many Ldl receptors become localized in the clathrin-coated pits. Both Ldl and its receptors are internalized by endocytosis to form a vesicle within the cell which then fuses with the lysosome containing lysosomal acid lipase that hydrolyzes cholesterol esters. At this stage cholesterol can be used for the biosynthesis of membrane and can be stored within the cell.

Synthesis of Ldl receptor is regulated by Srebp protein. When the cell has adequate estimate of cholesterol, Ldl receptor synthesis is blocked and no more molecules of cholesterol can enter inside the cell. When the cell is deficient in cholesterol more Ldl receptors are formed. When this law is deregulated more Ldl molecules without Ldl receptors appear in the bloodstream especially near the peripheral tissues. These molecules are then oxidized and taken up by the macrophages forming foam cells and contributing in the formation of atherosclerotic plaques on the walls of the arteries causing heart attack. Hdl molecules partake in reverse cholesterol transport as they return cholesterol back to the liver for excretion. Cholesterol is susceptible to oxidation and can of course form oxysterols that are the oxygenated derivatives. Oxysterols can be generated through three mechanisms especially by autoxidation, secondary oxidation to lipid peroxidation and cholesterol metabolizing enzyme oxidation. Oxysterols also partake in bile acid biosynthesis, transport of distinct forms of cholesterol and regulation of gene transcription.

Cholesterol is oxidized by the liver into a range of bile acids which are in turn conjugated with glycine, taurine, glucuronic acid. A mixture of both conjugated as well as non-conjugated bile acids along with cholesterol is excreted from the liver into bile. About 95% of the bile acids are reabsorbed from the intestines while rest is lost in faeces. The urination and reabsorption of bile acids form the basis of enterohepatic circulation requisite for digestion and absorption of the dietary fats. In positive circumstances, cholesterol crystallizes and forms gallstones especially in the gallbladder. Lecithin and bilirubin gallstones are also known to occur but their percentage is low. Everyday about 1 g of cholesterol is known to enter the colon which comes from diet, bile, desquamated intestinal cells and can be metabolized by the colonic bacteria. Cholesterol is generally converted into coprostanol which is a nonabsorbable sterol excreted in faeces. A cholesterol reducing bacterium has also been isolated from human faeces. Some cholesterol derivatives are known to create liquid crystalline cholesteric phase.

Dietary sources of cholesterol

Animal fats are involved mixtures of triglycerides having lower proportions of phospholipids and cholesterol. Major dietary sources of cholesterol comprise cheese, egg yolks, beef, pork, shrimp and poultry. Human breast milk also contains adequate amounts of cholesterol. The estimate cholesterol present in the plant sources is lesser when compared with the animal sources. Plant products like peanuts and flax seeds bear phytosterols which are cholesterol like compounds helping to lower serum cholesterol levels. The total fat intake especially in the form of saturated and trans fats play greater role in blood cholesterol rather than the intake of cholesterol itself. Saturated fats are abundantly present in the full fat dairy products, animal fats, chocolate and some types of oils.

Trans fats are obtained by the partial hydrogenation of unsaturated fats and do not occur in requisite amounts in nature. They are present in good amounts in the margarine, hydrogenated vegetable fats and in many fast foods like snacks, fried or baked goods. Avoiding consumption of cholesterol rich animal products not only reduces the estimate of cholesterol taken through the diet but also reduces the synthesis of cholesterol. Individuals interested to sacrifice their cholesterol levels through diet must consume less than 7% of their daily power needs from the animal fats and fewer than 200 mg of cholesterol per day. It is debatable that reduced consumption of dietary fat and cholesterol can lower blood cholesterol levels because any declination in the dietary uptake of cholesterol is compensated by the organs involved in its synthesis so that the levels can be kept constant.

Foods that might cholesterol

Dietary fibers play a major role in maintaining our health as well as also safe us from a estimate of diseases like diabetes and heart diseases. Oats, oat bran and oat meal comprise a special type of soluble fiber known as beta-glucan that helps in reducing the levels of Ldl cholesterol. Oat fibers are distinct from other fibers in the manner that they sacrifice the levels of bad cholesterol while the levels of good cholesterol remain unchanged. So we can say that oat fibers help in reducing the risk of coronary heart disease. Studies have also indicated that if individuals with high levels of Hdl consume 3 g of soluble oat fiber per day the total cholesterol levels may be declined. Soy protein also protects against heart diseases and hypercholesterolemia as it reduces the bad cholesterol and raises the good cholesterol. It also prevents the oxidation of bad cholesterol so that it may not coagulate on the arterial walls.

Several studies have indicated that drinking of green or black teas also sacrifice the blood cholesterol concentration, blood pressure and inhibit blood clotting and also provide some protection against cardiovascular diseases. Green tea is rich in catechins while black tea contains flavins that inhibit oxidation of bad cholesterol. Tea also contains folic acid that helps in reducing the risk of heart strike and cancer. A man can get 25% of Rda for folic acid by drinking five cups of tea in a day. some studies have indicated that barely has some unique health promoting effects especially for the heart. The cholesterol fighting efficiency of barley is more pronounced than that of oats. Studies have indicated that it can sacrifice up to 15% of total cholesterol levels in individuals with elevated cholesterol levels. Barley is also a rich source of beta-glucan which retards fat and cholesterol absorption by the intestines. The fiber is known to bind bile salts and thus, removes cholesterol from the body. Psyllium husk is also a rich source of soluble and insoluble fibers known to sacrifice the risk of cardiovascular diseases, serum cholesterol, Ldl levels, triglycerides and apolipoprotein B. Psyllium husk is rich in a fiber known as beta-sitosterol.

Cholesterol testing and reducing high cholesterol

The American Heart connection recommends that the cholesterol levels of individuals above 20 years of age must be checked in every five years. A blood sample after 12-hour fasting is taken by the curative specialist for the determination of the lipoprotein profile. This determines Ldl, Hdl, total cholesterol and triglyceride levels. Causes of high cholesterol may vary from man to man and are influenced by the lifestyle and gender of an individual. A estimate of steps can be taken in order to sacrifice high cholesterol levels for example loss of inordinate body weight. Avoidance of consumption of foods derived from animal fats, regular physical operation and rehearsal can also help in maintaining low cholesterol levels. Levels of cholesterol in both males and females increase after a positive age and the levels in women tend to increase after menopause. Genes also play an foremost role in a person's health.

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Weight Loss Shake Recipes - simple Recipes to Help You Lose Weight

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It is wonderful what you can do with a fridge full of fresh fruit and a blender. The contrast between blender recipes and juicing is the added benefit of soft fibers.

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This is wonderful for cleaning and maintaining a wholesome colon. Blender recipes are an perfect increasing to a medical and cleansing program.

Apricot Pineapple Smoothie Recipe

1/4 cup crushed pineapple
1 fresh apricot, diced
6 strawberries
1/2 banana
1 1/2 cup water
1 tbsp. Skim milk powder
1 heaping tbsp. High- potential protein powder (optional)
1 tsp. Flax seed oil (optional)

In a blender, process fruit with the rest of the ingredients. Blend until thoroughly mixed and serve.

Banana-Strawberry Fruit Smoothie Recipe

1 banana, frozen
6 strawberries, frozen
1 1/4 cup water
1 tbsp. Skim milk powder
1 heaping tbsp. High- potential protein powder (optional)
1 tsp. Flax oil (optional)

In a blender, process all the ingredients until thoroughly mixed and serve.

Tropical Fruit Shake

1/2 mango
2 tbsp. Frosty pina coloda mix (or 1/8 tsp. Natural coconut extract)
1/2 banana, frozen
4 strawberries, frozen
6 ice cubes
1 1/4 cup water
1 heaping tbsp. High- potential protein powder (optional)
1 tsp. Flax oil (optional)

In a blender, process all the ingredients until thoroughly mixed and serve.

Banana-Berry Fruit Smoothie

1/2 pear, cored
1/4 cup Frosty blueberries or Frosty mixed berries
1/2 banana, frozen
1 1/4 cup water
1/8 tsp. Cinnamon
1 tbsp. Skim milk powder
1 heaping tbsp. High-quality protein powder (optional)
1 tsp. Flax oil (optional)

In a blender, process all the ingredients until thoroughly mixed and serve.

Banana-Orange-Strawberry Fruit Shake

1/2 cup orange juice
1/2 banana, frozen
6 strawberries, frozen
1/2 cup water
1 tbsp. Skim milk powder
1 heaping tbsp. High- potential protein powder (optional)
1 tsp. Flax oil (optional)

In a blender, process all the ingredients until thoroughly mixed and serve.

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newest Study: Diabetes Drugs Don't Work, Diet and practice Are Still Best

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According to a up-to-date study the latest "magic bullet" drug therapy for diabetes and heart disease does not come close to working as advertised. In fact, researchers found that the blend of the high blood pressure drug Diovan (valsartan) and the anti-diabetes drug Starlix (nateglinide) failed to sell out the risk of heart assault at all and Diovan was only slightly flourishing in slowing the development of type Ii diabetes.

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Lead researcher Robert M Califf from Duke University School of treatment stated: "This is a sobering confirmation of the need to continue to focus on lifestyle improvements."

In the study published in the New England Journal of Medicine, researchers found that when compared to a placebo, valsartan and nateglinide failed to statistically sell out the incidence of either extended cardiovascular risk or core cardiovascular risk. The cumulative incidence of diabetes was 33.1% in the valsartan group, as compared with 36.8% in the placebo group.

Type Ii diabetes is known as a "lifestyle disease" because it is brought on by eating processed foods, junk foods and fast foods. It affects around 150 million population around the world and has come to be The lifestyle disease of contemporary times. Agreeing to doctors, the two main risk factors are excess weight and lack of exercise.

Some research has suggested that being overweight, as measured by body mass index (Bmi), is the many risk factor for diabetes. For example, researchers from Brigham and Women's Hospital in Boston conducted a study on 37,878 women who had no diabetes and found that women who were overweight had their diabetes risk growth by nine times. By comparison, those who were relatively inactive only increased their risk by less than one times. What the study evidently did not part was the kind of foods that led to being overweight. In other words, was the weight growth from relatively wholesome food items or was it due to consumption of unhealthy foods, as was likely?

The lowest line is that the best guidance for avoiding diabetes is to have both a wholesome diet and a healthy, active lifestyle. A sensible diet to help avoid diabetes would be one that includes plentifulness of vegetables, especially raw and lightly steamed vegetables, some fruits (though little or no fruit juice because of its high sugar content), fermented whole grains, and getting rid of perilous trans fats. Other good food items contain almonds, apples, oranges, coconut oil, garlic, onions, and substances high in omega three oils (such as olive oil, flaxseed oil and fish oil).

Exercise to keep diabetes at bay need not be strenuous. Moderate rehearsal such as daily brisk walks and staying active should be plentifulness for most people, though those that are seriously overweight may want to rehearsal a bit more and restrict their fat to sell out their weight. Even an authentically achievable weight loss of 5% has been shown to have valuable condition benefits, and for many population that might require little more than quarterly walking and eliminating sugary sodas.

An often overlooked item in diabetes prevention is the point of sufficient iodine. Iodine is a key element in fighting diabetes because it helps regulate the thyroid and is valuable for a wholesome liver, gallbladder, pancreas, spleens and more. While it is well known that diet, obesity, food allergies, viral infections, and stress are all contributing factors for diabetes, it is less widely recognized that these factors are often either a cause of or caused by a weak liver, spleen, and pancreas.

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I Hate to rehearsal - Ok, Do This Instead If You're Desperate to Lose Weight fast

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You're desperate to lose weight quickly, but you say "I hate to exercise". So what to do? I'll let you in on some private "Shortcuts" so that you can Cheat your way to fast weight loss.

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I Hate To practice Also, So Join the Club

Secret #1: Rinse yourself with cold water daily

Listen, I'd tell you to take cold showers but I know you plainly can't cope it. So take your normal shower. But then turn the water to unmistakably cold and rinse off for 15-20 seconds. That's it.

What this does is it causes the body to go right into thermogenesis (burn fat for energy and heat). Tadaaa, instant fat loss. Results come fast and furious if you do this everyday. I hate to practice just like you... So I found ways colse to it.

Secret #2: Never, ever drink a liquid with a meal

Look, you have natural enzymes that breakdown foods when you're eating. But if you drink something while you're eating, you dilute those enzymes and render them useless.

Food then doesn't get digested properly. You get constipation, indigestion, and a bunch of other things... Also hurting your weight loss efforts.

You need your digestive theory to be running at peak efficiency to get the most weight loss possible. So drink your liquids 5-10 minutes before and after a meal.

Secret #3: Take Extra Virgin Coconut Oil

This is a "good" fat. In fact, the body virtually takes this fat and converts it into energy practically instantly. Because this is a short article, I can't get too much into the mental behind why extra virgin coconut oil works for fat loss.

But here's a fact... My clients who take it lose on mean 5-6 pounds in 11-13 days. By the way, 1 jar of the stuff costs about and will last for 13 days.

Just take the extra virgin coconut oil twice a day on an empty stomach between meals. Morning and afternoon are best.

So there you go. I hate to practice just like you. I did my homework and tested this all out for you. It all works. If you're desperate to lose weight quickly, then I extremely advise you start doing these 3 things.

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Weight Loss Programs

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Weight loss programs come in many different shapes and sizes. Some of your options are: purchasing a membership at a local fitness center, joining a weight loss sustain group, buying a schedule online, naturally going on a diet, or just increasing exercise. Just because it says "weight loss programs" doesn't mean it has to be something bought or something with a routine. That part is up to you. It all boils down to the same thing; you want to become healthier by losing weight.

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How is Weight Loss Programs

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If you're the type of person that needs sustain while your "journey", then maybe a fitness town is your best choice. You get to meet a lot of new people whom are on a similar journey. You can meet with them on a daily or weekly basis and hold your 'teammates' accountable for their success or laziness. Push them to do their best, the favor will be returned. Most of the time, the fitness town will have an practice and diet plan for you to go by. Set goals for yourself and strive for them, it's great to set more, smaller goals than few big goals. This is a way for you to stay determined and keep you going strong.

Even though there are some types of sustain systems and the fitness center, sustain groups, which are a bit different don't wish you to "weigh in" or succeed an practice and diet plan. But it does have one thing in base with the sustain ideas at the fitness center. You hold each other accountable for all of your actions whether they are good or bad. It all the time helps to find people that are on the same journey as you so you can share some of your successes and even some of your failures so you are able to learn from them.

Then there are the weight loss programs that are centered colse to prepackaged foods. This route can be pursued online or even at a fitness town as stated above. One of the advantages to this is that the portions are set for you. This thoroughly eliminates part measuring and calorie counting. This helps out the people who don't have adequate time to count calories, part the food, put in order it, and then enjoy it. However, we all know that some of the 'healthier' foods don't taste the best. No one likes eating salads every day and such. Also, these types of programs can get a bit pricy and can cost upwards of 0+ per month. Obviously these types of programs aren't for you. But if you think you could do it, more power to you.

No matter which weight loss schedule you choose, make sure you don't look back. Pick one that suits you and run with it. Before you know it, your life will be changed.

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Coconut Oil For Weight Loss

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Is it true that you can eat coconut oil for weight loss? Many population view that this oil (primarily containing saturated fat) bears the same fatty chain structure as animal saturated fats. Here's the incompatibility - animal saturated fat molecules attach to one another in long chain which your body finds hard to break down and thus store it as fat very easily, whereas coconut oil's saturated fat molecules form medium chain structure and readily breaks down for vigor use during digestion.

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How is Coconut Oil For Weight Loss

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This in turn boosts your metabolism and burn fat off your fat storage. That explains why most population drop their pants size from eating coconut oil for weight loss.

In case you view this fat-burning oil might get stocked up into your fat storage like any other vegetable or animal fats, here's the fact: Saturated fat in coconut oil, or ordinarily referred to as medium-chain fatty acids (Mcfas), reacts differently from other dietary fats. The Mcfas voyage along the bloodstream level to the liver, where they're immediately processed and converted into energy, just like carbohydrate. Hence, they won't get stored as fat so no ifs ands or buts and cause weight gain.

Here's another big benefit of eating coconut oil for weight loss. Being smaller in size, Mcfas together with other vigor components in the oil yield fewer fat than other fats - only 8.62 fat per gram. This means if you replace other oils (which carry 9 fat per gram) with coconut oil, you'll benefit from lower calorie intake.

Remember that I said earlier that curious coconut oil for weight loss can stimulate your metabolism? imagine your metabolism speeds up, at the same time you're ingesting lower calories, you can expect to burn more fat off your excess fat stores. That's how you can lose weight effectively with this medium-chain fat-burning oil.

How to Eat Coconut Oil for Weight Loss

But here's the kicker. No matter how fat-burning the oil is, like any other foods, when you consume excess of it which the level of your metabolism is not able to burn it off totally, extra fat that left unused will still get deposited as fat in your vigor bank. Hence, consume the right amount and you'll lose fat effectively.

When you're beginning out with eating the oil for weight loss, because this fat-burning oil is highly efficient in curing constipation, you should take up 1 tablespoon (1/2 in morning, 1/2 at night) first for at least 7 days. Seek your body health and if you feel it works well with you, up the intake to 2 and then progressively to 3 tablespoons later on. After any months when you feel you can ingest more, you can no ifs ands or buts growth the intake up to 5 tablespoons spread out in a day. Adding it to your diet progressively is the key to good health and shape.

That's what you should do when using coconut oil for weight loss. If you up the amount too fast, the oil may give you a diarrhea effect. So, work with your body closely for maximum fat loss without risking your health. Any food that's good when eat in the wrong way can influence you negatively. Bear in mind.

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